I-Psoriasis, isifo sesikhumba esingapheli, esiphindaphindayo, esivuvukalayo futhi esihlelekile esibangelwa imiphumela yofuzo kanye nemvelo.I-Psoriasis ngaphezu kwezimpawu zesikhumba, kuzoba ne-cardiovascular, metabolic, digestive and malignant tumors nezinye izifo eziningi. Nakuba ingatheleleki, ilimaza kakhulu isikhumba futhi inomthelela omkhulu ekubukeni, okuletha umthwalo omkhulu ngokomzimba nangokwengqondo ezigulini futhi kuthinta kakhulu izinga lokuphila.
Ngakho-ke, i-ultraviolet phototherapy iphatha kanjani i-psoriasis?
1.Tyena ukwelashwa ezivamile psoriasis
Imithi ye-topical iwukwelashwa okuyinhloko kwe-psoriasis emaphakathi kuya kwemaphakathi. Ukwelashwa kwezidakamizwa ze-topical kuncike eminyakeni yesiguli, umlando, uhlobo lwe-psoriasis, inkambo yesifo kanye nezilonda.
Izidakamizwa ezivame ukusetshenziswa yi-glucocorticoids, i-vitamin D3 derivatives, i-retinoic acid nokunye. Ukusetshenziswa okuhlelekile kwezidakamizwa zomlomo noma i-biologics efana ne-methotrexate, i-cyclosporine ne-retinoic acid kunconywa ezigulini ezine-scalp psoriasis ezihambisana nezilonda ezilinganiselwe kuya ezinzima.
2.Tizici ze-ultraviolet phototherapy
I-Ultraviolet phototherapy iyindlela yokwelapha enconyelwa kakhulu ye-psoriasis ngaphezu kwezidakamizwa. I-Phototherapy ikakhulukazi idala i-apoptosis yamaseli e-T ezilonda ze-psoriatic, ngaleyo ndlela ivimbele amasosha omzimba asebenze ngokweqile futhi ikhuthaze ukuhlehla kwezilonda.
Ihlanganisa ikakhulukazi i-BB-UVB(>280~320nm), i-NB-UVB(311±2nm), i-PUVA(ukugeza ngomlomo, okokwelapha kanye nendawo) kanye nezinye izindlela zokwelapha.Umphumela wokwelapha we-NB-UVB wawungcono kune-BB-UVB futhi ubuthakathaka. kune-PUVA ekwelapheni kwe-UV kwe-psoriasis. Kodwa-ke, i-NB-UVB iyindlela yokwelapha evame ukusetshenziswa kakhulu emisebeni ye-ultraviolet enokuphepha okuphezulu nokusetshenziswa kalula. Ukwelashwa kwe-UV ye-topical kunconywa uma indawo yesikhumba ingaphansi kwe-5% yendawo yonke yomzimba.Lapho indawo yesikhumba inkulu kune-5% yendawo yomzimba, ukwelashwa kwe-UV okuhlelekile kunconywa.
3.Ukwelashwa kwe-NB-UVB kwe-psoriasis
Ekwelapheni i-psoriasis, ibhande eliyinhloko elisebenzayo le-UVB likububanzi obungu-308~312nm. Ibhande elisebenzayo le-NB-UVB(311±2nm) ekwelapheni i-psoriasis limsulwa kakhulu kunele-BB-UVB(280~320nm), futhi umphumela ungcono, eduze nomphumela we-PUVA, futhi unciphisa ukusabela kwe-erythematous. okubangelwa ibhendi engasebenzi. Ukuphepha okuhle, akukho ukuhlangana nomdlavuza wesikhumba okutholakele. Njengamanje, i-NB-UVB iyisicelo somtholampilo esithandwa kakhulu ekwelapheni i-psoriasis.
Isikhathi sokuthumela: Feb-16-2023
