I-Psoriasis ivamile, eminingi, kulula ukuphinda ibuyele emuva, kunzima ukwelapha izifo zesikhumba okuthi ngaphezu kokwelashwa kwezidakamizwa zangaphandle, ukwelapha oral systemic, ukwelashwa kwebhayoloji, kukhona okunye ukwelashwa ukwelapha ngokomzimba. I-UVB phototherapy iwukwelapha ngokomzimba, Ngakho-ke yimiphi imiphumela emibi ye-UVB phototherapy ye-psoriasis?
Iyini i-UVB phototherapy? Yiziphi izifo ezingelashwa ngayo?
I-UVB phototherapysebenzisa umthombo wokukhanya wokwenziwa noma amandla emisebe yelanga ukwelapha izifo, kanye nokusetshenziswa kwemisebe ye-ultraviolet emzimbeni womuntu wokwelapha indlela yesifo ebizwa ngokuthi i-ultraviolet therapy. Umgomo we-UVB phototherapy ukuvimbela ukwanda kwamaseli e-T esikhumbeni, ukuvimbela i-epidermal hyperplasia nokuqina, ukunciphisa ukuvuvukala kwesikhumba, ukuze kunciphise ukulimala kwesikhumba.
I-UVB phototherapy inomphumela omuhle ekwelapheni izifo ezihlukahlukene zesikhumba, njenge-psoriasis, i-dermatitis ethize, i-vitiligo, i-eczema, i-bryophyid pityriasis engapheli, njll. Phakathi kwazo ekwelapheni i-psoriasis ukuthi i-UVB (i-wavelength ye-280-320 nm) idlala a indima enkulu, ukuhlinzwa ukudalula isikhumbaukukhanya kwe-ultravioletngesikhathi esithile; I-Phototherapy ye-UVB inezakhiwo ezahlukene ezifana ne-anti-inflammatory, immunosuppression kanye ne-cytotoxicity.
Yiziphi izigaba ze-phototherapy?
I-Psoriasis optical therapy inezinhlobo ezi-4 zokuhlukanisa, ngokulandelana kwe-UVB, NB-UVB, PUVA, i-excimer laser treatment. Phakathi kwazo, i-UVB ilula kakhulu futhi ishibhile kunezinye izindlela ze-phototherapy, ngoba ungakwazisebenzisa i-UVB phototherapy ekhaya. I-UVB phototherapy ngokuvamile inconywa kubantu abadala kanye nezingane ezine-psoriasis. Uma izilonda ze-psoriasis zenzeka ezindaweni ezincane, umphumela we-phototherapy uzoba sobala
Yiziphi izinzuzoI-UVB phototherapy ye-psoriasis?
I-UVB phototherapy ifakiwe ekuxilongweni kwe-psoriasis nemihlahlandlela yokwelashwa (uhlelo lwe-2018), futhi umphumela wayo wokwelapha uqinisekile. Izibalo zibonisa ukuthi u-70% kuya ku-80% weziguli ze-psoriasis zingathola ukukhululeka kwezilonda zesikhumba ngo-70% kuya ku-80% ngemva kwezinyanga ezingu-2-3 ze-phototherapy evamile.
Kodwa-ke, akuzona zonke iziguli ezifanele i-phototherapy. I-Mild psoriasis yelashwa kakhulu ngemithi ephathwayo, kuyilapho i-UVB phototherapy iyindlela yokwelapha ebaluleke kakhulu ezigulini ezilinganiselayo neziqinile.
I-Phototherapy ingandisa isikhathi sokuphindaphinda kwesifo. Uma isimo sesiguli sincane, ukuphindaphinda kungagcinwa izinyanga ezimbalwa. Uma lesi sifo sinenkani futhi kunzima ukususa izilonda zesikhumba, ingozi yokuphindaphinda iphakeme, futhi izilonda zesikhumba ezintsha zingase zenzeke ezinyangeni ezingu-2-3 ngemva kokumisa i-phototherapy. Ukuze kube nomphumela ongcono wokwelapha futhi kuncishiswe ukuphindeka, i-phototherapy ivamise ukusetshenziswa kanye nemithi ethile ye-topical ekusebenzeni komtholampilo.
Ocwaningweni lokuqaphela ukusebenza kwe-tacathinol ointment ehlanganiswe nemisebe emincane ye-UVB ekwelapheni i-psoriasis vulgaris, iziguli ezingama-80 zabelwa eqenjini elilawulayo elathola i-UVB phototherapy iyodwa kanye neqembu lokwelapha elathola i-tacalcitol topical (kabili ngosuku) lihlanganisiwe. nge-UVB phototherapy, i-radiation yomzimba, kanye njalo ngolunye usuku.
Imiphumela yocwaningo ibonisa ukuthi kwakungekho umehluko ophawulekayo wezibalo wamaqembu amabili eziguli ezine-PASI amaphuzu kanye nokusebenza kahle kokwelashwa kuze kube isonto lesine. Kodwa uma kuqhathaniswa nokwelashwa kwamasonto angu-8, iqembu lokwelapha le-PASI amaphuzu (i-psoriasis skin lesion degree score) lithuthukisiwe futhi lisebenza kahle lalingcono kuneqembu lokulawula, liphakamisa ukuthi i-tacalcitol joint UVB phototherapy ekwelapheni i-psoriasis inomphumela omuhle kune-UVB phototherapy kuphela.
Yini i-tacacitol?
I-Tacalcitol iphuma kuvithamini D3 esebenzayo, futhi izidakamizwa ezifanayo zine-calcipotriol ecasulayo enamandla, enomphumela ovimbela ukwanda kwamangqamuzana e-epidermal. I-Psoriasis ibangelwa ukwanda ngokweqile kwamangqamuzana e-epidermal glial, okuholela ku-erythema kanye ne-silvery white desquamate esikhumbeni.
I-Tacalcitol imnene futhi iyacasula kancane ekwelapheni i-psoriasis (i-psoriasis ye-intravenous nayo ingayisebenzisa) futhi kufanele isetshenziswe izikhathi ezingu-1-2 ngosuku kuye ngobunzima besifo. Kungani usho ngobumnene? Ezingxenyeni ezincane nezithambile zesikhumba, ngaphandle kwe-cornea kanye ne-conjunctiva, zonke izingxenye zomzimba zingasetshenziswa, kuyilapho ukucasuka okunamandla kwe-calcipotriol kungasetshenziswa ekhanda nasebusweni, ngoba kungase kube nokuluma, i-dermatitis, i-edema. eduze kwamehlo noma i-edema ebusweni nokunye ukusabela okungekuhle. Uma ukwelashwa kuhlanganiswe ne-UVB phototherapy leyo phototherapy iba kathathu ngesonto, kanye ne-tacalcitol kabili ngosuku
Imuphi umphumela ohlangothini ongaba nawo i-UVB phototherapy? Yini okufanele inake ngesikhathi sokwelashwa?
Ngokuvamile, imiphumela emibi eminingi yokwelashwa kwe-UVB ingeyesikhashana, njengokuluma, ukusha noma amabhamuza. Ngakho-ke, ngengxenye yezilonda zesikhumba, i-phototherapy idinga ukumboza isikhumba esinempilo kahle. Akulungile ukugeza ngokushesha ngemva kwe-phototherapy, ukuze unganciphisi ukumuncwa kwe-Uv kanye ne-phototoxicity.
Ngesikhathi sokwelashwa akufanele udle izithelo nemifino e-photosensitive: umkhiwane, i-coriander, umcako, ulethisi, njll; Futhi awukwazi ukuthatha umuthi ozwelayo: i-tetracycline, i-sulfa drug, i-promethazine, i-chlorpromethazine hydrochloride.
Futhi ukudla okubabayo okucasulayo okungase kubangele isimo sibe sibi, udle kancane ngangokunokwenzeka noma ungadli, lolu hlobo lokudla lunokudla kwasolwandle, ugwayi notshwala, njll., ngokulawula okunengqondo kokudla kungakhuthaza ukubuyiswa kwezilonda zesikhumba. , futhi kuvimbele ngokuphumelelayo ukuphindaphinda kwe-psoriasis.
Isiphetho: I-Phototherapy ekwelapheni i-psoriasis, inganciphisa izilonda ze-psoriasis, inhlanganisela enengqondo yezidakamizwa ze-topical ingathuthukisa umphumela wokwelapha futhi inciphise ukuphindaphinda.
Isikhathi sokuthumela: Jun-07-2022
