I-Psoriasis iyinto evamile, eminingi, elula ukuyiphinda, kunzima ukuyilapha izifo zesikhumba okuthi ngaphezu kokwelashwa ngemithi yangaphandle, ukwelashwa ngomlomo, ukwelashwa kwezinto eziphilayo, kukhona okunye ukwelashwa ngokomzimba. I-UVB phototherapy iwukwelashwa ngokomzimba, Ngakho-ke yimiphi imiphumela emibi ye-UVB phototherapy ye-psoriasis?
Kuyini ukwelashwa nge-UVB phototherapy? Yiziphi izifo ezingelashwa yiyo?
Ukwelashwa nge-UVBsebenzisa umthombo wokukhanya okwenziwe noma amandla emisebe yelanga ukwelapha izifo, kanye nokusebenzisa imisebe ye-ultraviolet emzimbeni womuntu indlela yokwelapha isifo ebizwa ngokuthi i-ultraviolet therapy. Isimiso se-UVB phototherapy ukuvimbela ukwanda kwamaseli e-T esikhumbeni, ukuvimbela i-epidermal hyperplasia kanye nokuqina, ukunciphisa ukuvuvukala kwesikhumba, ukuze kuncishiswe umonakalo wesikhumba.
Ukwelashwa nge-UVB kunomphumela omuhle ekwelapheni izifo zesikhumba ezahlukahlukene, njenge-psoriasis, i-dermatitis ethile, i-vitiligo, i-eczema, i-bryophyid pityriasis engapheli, njll. Phakathi kwazo ekwelapheni i-psoriasis ukuthi i-UVB (ubude bamagagasi angu-280-320 nm) idlala indima enkulu, umsebenzi uwukuveza isikhumba ku-ukukhanya kwe-ultravioletngesikhathi esithile; i-UVB phototherapy inezakhiwo ezahlukene njengokulwa nokuvuvukala, ukucindezela amasosha omzimba kanye ne-cytotoxicity.
Yiziphi izinhlobo ze-phototherapy?
Ukwelashwa nge-Psoriasis optical kunezinhlobo ezine zokuhlukaniswa, ngokulandelana kwe-UVB, NB-UVB, PUVA, kanye nokwelashwa nge-laser excimer. Phakathi kwazo, i-UVB ilula kakhulu futhi ishibhile kunezinye izindlela ze-phototherapy, ngoba ungakwazisebenzisa i-UVB phototherapy ekhayaUkwelashwa nge-UVB kuvame ukunconywa kubantu abadala nezingane ezine-psoriasis. Uma izilonda ze-psoriasis zenzeka ezindaweni ezincane, umphumela we-phototherapy uzoba sobala.
Yiziphi izinzuzo ze-Ukwelashwa nge-UVB kwe-psoriasis?
Ukwelashwa nge-UVB kufakiwe eziqondisweni zokuxilongwa kanye nokwelashwa kwe-psoriasis (uhlelo luka-2018), futhi umphumela wayo wokwelapha uqinisekile. Izibalo zibonisa ukuthi iziguli ze-psoriasis ezingama-70% kuya ku-80% zingafinyelela ukukhululeka okungu-70% kuya ku-80% kwezilonda zesikhumba ngemva kwezinyanga ezingu-2-3 zokwelashwa nge-phototherapy okuvamile.
Kodwa-ke, akuzona zonke iziguli ezifanele ukwelashwa nge-phototherapy. I-psoriasis encane iphathwa kakhulu ngemithi yokwelapha, kanti i-UVB phototherapy iyindlela yokwelapha ebaluleke kakhulu ezigulini eziphakathi nendawo nezinzima.
Ukwelashwa nge-Phototherapy kungandisa isikhathi sokuphindeka kwesifo. Uma isimo sesiguli sincane, ukuphinda kuvele kungagcinwa izinyanga eziningana. Uma isifo siqinile futhi izilonda zesikhumba kunzima ukuzisusa, ingozi yokuphinda kuvele iphezulu, futhi izilonda zesikhumba ezintsha zingase zenzeke ezinyangeni ezingu-2-3 ngemva kokuyeka ukwelashwa nge-phototherapy. Ukuze kube nomphumela ongcono wokwelapha nokunciphisa ukuphinda kuvele, ukwelashwa nge-phototherapy kuvame ukusetshenziswa kanye neminye imithi esetshenziswa emtholampilo.
Esifundweni sokubuka ukusebenza kahle kwamafutha e-tacathinol ahlanganiswe nemisebe ye-UVB emincane ekwelapheni i-psoriasis vulgaris, iziguli ezingu-80 zabelwa eqenjini lokulawula elathola i-UVB phototherapy kuphela kanye neqembu lokwelapha elathola i-tacalcitol topical (kabili ngosuku) kuhlanganiswe ne-UVB phototherapy, ukushiswa kwemisebe emzimbeni, kanye njalo ngemva kosuku olulodwa.
Imiphumela yocwaningo ikhombisa ukuthi akukho mehluko obalulekile ngokwezibalo phakathi kwamaqembu amabili eziguli ezine-PASI score kanye nokusebenza kahle kokwelashwa kuze kube yisonto lesine. Kodwa uma kuqhathaniswa nokwelashwa kwamasonto ayi-8, i-PASI score yeqembu lokwelashwa (i-psoriasis skin lesion degree score) ithuthukisiwe futhi isebenza kahle kakhulu kuneqembu lokulawula, iphakamisa ukuthi i-tacalcitol joint UVB phototherapy ekwelapheni i-psoriasis inomphumela omuhle kune-UVB phototherapy kuphela.
Iyini i-tacacitol?
I-Tacalcitol iwumkhiqizo we-vitamin D3 esebenzayo, futhi imithi efanayo ine-calcipotriol enamandla ecasulayo, enomphumela wokuvimbela ukwanda kwamaseli e-epidermal. I-Psoriasis ibangelwa ukwanda ngokweqile kwamaseli e-glial e-epidermal, okuholela e-erythema kanye ne-desquamate emhlophe esiliva esikhumbeni.
I-Tacalcitol ithambile futhi ayicasuli kangako ekwelapheni i-psoriasis (i-psoriasis efakwa emithanjeni nayo ingayisebenzisa) futhi kufanele isetshenziswe izikhathi ezingu-1-2 ngosuku kuye ngokuthi lesi sifo sibucayi kangakanani. Kungani kufanele isetshenziswe ithambile? Ezingxenyeni ezincane nezithambile zesikhumba, ngaphandle kwe-cornea kanye ne-conjunctiva, zonke izingxenye zomzimba zingasetshenziswa, kuyilapho ukucasuka okukhulu kwe-calcipotriol kungasetshenziswa ekhanda nasebusweni, ngoba kungase kube nokulunywa, i-dermatitis, ukuvuvukala okuzungeze amehlo noma ukuvuvukala kobuso kanye neminye imiphumela emibi. Uma ukwelashwa kuhlanganiswe ne-UVB phototherapy, leyo phototherapy isetshenziswa kathathu ngesonto, kanye ne-tacalcitol kabili ngosuku.
Yimuphi umphumela ongemuhle ongaba nawo nge-UVB phototherapy? Yini okufanele uyinake ngesikhathi sokwelashwa?
Ngokuvamile, imiphumela eminingi emibi yokwelashwa kwe-UVB ingeyesikhashana, njengokulunywa, ukusha noma amabhamuza. Ngakho-ke, ngokwengxenye izilonda zesikhumba, ukwelashwa nge-phototherapy kudinga ukumboza kahle isikhumba esinempilo. Akufanelekile ukugeza ngokushesha ngemva kokwelashwa nge-phototherapy, ukuze kunganciphisi ukumuncwa kwe-UV kanye nobuthi be-phototoxicity.
Ngesikhathi sokwelashwa akufanele udle izithelo nemifino ezwela ukukhanya: umkhiwane, i-coriander, i-lime, i-lettuce, njll.; Futhi awukwazi ukuthatha umuthi ozwela ukukhanya: i-tetracycline, i-sulfa drug, i-promethazine, i-chlorpromethazine hydrochloride.
Futhi ngokudla okunongwe okucasulayo okungabangela ukubhebhetheka kwalesi simo, ungadli kakhulu ngangokunokwenzeka noma ungadli, lolu hlobo lokudla lunokudla kwasolwandle, ugwayi notshwala, njll., ngokulawula ukudla okunengqondo kungakhuthaza ukululama kwezilonda zesikhumba, futhi kuvimbele ngempumelelo ukuphinda kwe-psoriasis.
Isiphetho: Ukwelashwa nge-Phototherapy ekwelapheni i-psoriasis, kunganciphisa izilonda ze-psoriasis, inhlanganisela efanele yemithi yasendaweni ingathuthukisa umphumela wokwelashwa futhi inciphise ukuphindaphinda kwesifo.
Isikhathi sokuthunyelwe: Juni-07-2022
